It was found that the expression levels of various genes involved in PGC-1α, fatty acid β-oxidation, and oxidative phosphorylation signaling pathways decreased in viral myocarditis, and these levels were significantly negatively correlated with the expression of pro-inflammatory cytokines (TNF-α) (Remels et al., 2018). This evidence concerns the gene PPARGC1A and viral myocarditis.