Consequently, selective FLT3 inhibitionis a promising strategy for FLT3-mutated AML., Huang et al. used a multivariate computational approach integratingmachine learning, molecular docking, and molecular dynamics to identify68 potential FLT3 inhibitors, starting from a Bemis-Murcko scaffoldanalysis on 1189 active molecules in the same target. The gene discussed is FLT3; the disease is acute myeloid leukemia.