Regarding the role of apoptosis, there are two different ongoing clinical trials in AIH patients listed on ClinicalTrials.gov, one studying the immunoproteasome inhibitor, zetomipzomib, and another studying an inhibitor of the receptor for B cell activating factor belonging to the tumor necrosis factor family, also known as a BAFF. The gene discussed is TNFSF13B; the disease is autoimmune hepatitis.