Sensitivity for diagnosing prostate adenocarcinoma with PSA level and NKX3.1 are nearly 100% and 88.3%, respectively, whereas CK34βE12, p63 and GATA3 are not usually present in prostatic adenocarcinoma (1.8%, 0% and 0%, respectively, in prostatic adenocarcinoma tissue) [8]. The gene discussed is NKX3-1; the disease is prostate adenocarcinoma.