INS and Hyperglycemia: In the study by Yao et al., systemic integration of patient data with varying levels of glycemic control showed that SCFA-producing Faecalibacterium, Roseburia, and Akkermansia were associated with improved insulin secretion and reduced glucose levels, whereas an abundance of Ruminococcus gnavus and Escherichia-Shigella correlated with hyperglycemia and impaired β-cell activity (Yao et al., 2024).