The results revealed several factors associated with higher frailty levels, including older age (OR = 1.125, 95% CI:1.011–1.253), underweight status (OR = 0.037, 95% CI:0.002–0.664), stress (OR = 1.696, 95% CI:1.309–2.196), insomnia (OR = 1.300, 95% CI:1.033–1.636), married status (OR = 0.004, 95% CI:0.003–0.600), elevated white blood cell count (OR = 1.591, 95% CI:1.078–2.349), and low albumin levels (OR = 0.770, 95% CI:0.623–0.953). The gene discussed is ALB; the disease is insomnia.