PELI3 and non-small cell lung carcinoma: A549 cells knocked down of PELI3 were also treated with Mebendazole, but we found that Mebendazole could not significantly increase the protein expression of TRADD in PELI3-silenced cells (Figures 5F, G), which further confirmed that Mebendazole stabilized TRADD through regulating PELI3 expression in NSCLC cells.