The top ten differentially expressed genes in this study include Gm29879, Lcn2, Cxcl10, Zbp1, Lbhd2, C5aR1, Cxcl10, Lbhd2, Cxcl9, and Fpr1, all of which might play a role in the pathophysiology of sepsis-induced WMI. Here, C5AR1 is linked to Sepsis.