The results of the K‒M curve analysis revealed that CRC patients with elevated expression levels of 8 specific genes (ANGPT2, CYP24A1, IFNE, PLAU, FRMD5, SERPINE1, ZBED2, and GSDMC) had unfavorable prognoses (Fig. 3D). The gene discussed is ANGPT2; the disease is colorectal carcinoma.