In addition to the changes in cancer cell behavior, we also observed increased neurite outgrowth of PC12 and NS20Y nerve cells when co-cultured with conditioned medium from LNCaP cells overexpressing Snail or C4-2 non-silencing cells compared to LNCaP Neo control or C4-2 Snail knockdown cells, respectively 13. This evidence concerns the gene SNAI1 and cancer.