In colorectal cancer, increased expression of LDHA, PKM2, and GLUT1, associated with glycolysis, was observed in c-Myc-overexpressing HCT116 cells, and the ECAR assay showed that the interference of far upstream element-binding protein 1 was reversed by c-Myc overexpression, resulting in the inhibition of glycolysis 114. This evidence concerns the gene MYC and colorectal cancer.