AFP and hepatocellular carcinoma: We further examined the diagnostic value of the four biomarkers in discriminating HCC patients from different controls, and the results are shown in Figure 2B-2D. When the LC group was used as the control group, the diagnostic performance of AFP, AFP-L3 and DCP decreased slightly compared with that of the HC and CHB groups, but the diagnostic performance of GP73 was greater than that of the CHB group.