First, it highlights the overlap between SPS and other autoimmune conditions: T1DM, like SPS, is associated with GAD65 autoantibodies (Bai et al., 2022, Trier et al., 2022), and the co-occurrence of these diseases underscores the need for comprehensive autoimmune screening in SPS patients. The gene discussed is GAD2; the disease is type 1 diabetes mellitus.