Within three PAAD datasets analysis of ONCOMINE, the transcription level of AMIGO2 in PAAD was significantly higher than normal tissues, with fold changes of AMIGO2 of 3.763 (P = 6.26E-14), 2.695 (P = 6.99E-5) and 3.421 (P = 2.42E-7), respectively (Table 1). Here, AMIGO2 is linked to pancreatic adenocarcinoma.