KLF5 and bladder transitional cell carcinoma: Validation with the UALCAN database further confirmed a significantly lower level of KLF 5 methylation in multiple tumor tissues including BLCA, HNSC, KIRC, KIRP, LUAD, LUSC, PAAD, THCA, UCEC (Figure 5C), implicating KLF5 PTMs in tumor-related regulatory mechanisms.