KLF5 and cancer: Pan-cancer analysis of KLF5 copy number variation (CNV) patterns, revealed a predominance of heterozygous amplification in which READ, STAD, ESCA, BLCA, and COAD, while the predominance of heterozygous deletion in HNSC, LGG, GBM, BRCA, PRAD, LUAD, KIRC, TGCT and OV (Figures 4D, E).