IGHG3 and infection: mAb46 expressed in the various scaffolds was able to effectively neutralize infection by the Wa strain, with a more pronounced – although not statistically significant (p-value > 0.05) – activity in IgG3 (IC50 = 0.013 μg/ml), dimeric IgA1 (IC50 = 0.054 μg/ml) and IgA2 (IC50 = 0.024 μg/ml) forms.