For example, MEX3A in the cytoplasm of CRC cells undergoes LLPS, interacts with circMPP6, and the MEX3A/circMPP6 complex recruits processing bodies, enhances the degradation of PDE5A mRNA, which facilitates proliferation and invasion, and suppresses CRC cell autophagy, thus resulting in poor survival outcomes in CRC patients (21). This evidence concerns the gene PDE5A and colorectal carcinoma.