Previous research has demonstrated that the miR-29 family is downregulated in diabetic nephropathy and diabetic cardiomyopathy [13,14], where it suppresses collagen gene expression (including COL1A1, COL4A1, and COL6A2) and is closely linked to TGF-β signaling [15]. The gene discussed is COL1A1; the disease is diabetic cardiomyopathy.