TTR and Familial transthyretin-related amyloidosis: Inheritance of a mutated transthyretin gene coding for a ‘variant’ and unstable transthyretin protein underpins hereditary transthyretin amyloidosis (ATTRv), whereas accelerated degradation of the genotypically normal, i.e., ‘wild-type’ protein in response to ageing describes ‘wild-type’ transthyretin amyloidosis (ATTRwt) [3].