Mutations in LDB3 gene have been also associated with muscular dystrophy (Selcen and Engel, 2005) and several cardiomyopathies (arrhythmogenic right ventricular, noncompaction and dilated cardiomyopathies) (Vatta et al., 2003; Arimura et al., 2004; Xi et al., 2012; Lopez-Ayala et al., 2014). Here, LDB3 is linked to cardiomyopathy.