2024). The folate and FR‐alpha/FOLR1 signalling axis have in different cancer cells been shown to activate multiple proliferative controlling kinases, for example, JAK/STAT, SRC and ERK (Nawaz and Kipreos 2022). Interestingly, FR‐alpha/FOLR1 has previously been reported to have a higher expression in LUAD cases with mutant EGFR (Iwakiri et al. 2008, Tamura et al. 2020, Nunez et al. 2012). This evidence concerns the gene EGFR and cancer.