We also analysed CSPG4 expression on EVs isolated from another EGFR‐mutant osimertinib resistant NSCLC cell line, HCC827/OR, by ELISA and observed a clear expression, albeit no difference of CSPG4 expression prior and post osimertinib treatment was seen (Figure S3). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.