The PTEN deletion rate increased markedly from pTaG2 low‐grade (3.1%), to pTaG2 high‐grade (4.5%) and pTaG3 (20.7%, p < 0.0001) carcinomas, and was 23.8% in pT2‐4 carcinomas (p < 0.0001 for pTa vs. pT2‐4). Here, PTEN is linked to carcinoma.