CXCL3 and hepatocellular carcinoma: Low levels of FTCD in HCC patients are associated with poor prognoses, while cirrhosis and low levels of FTCD are associated with a significantly higher risk of HCC.20 Hepatocellular carcinoma tumors that express high levels of CXCL3 are associated with a worse prognosis compared to those with low CXCL3 expression.