CRH and Hypoglycemia: At 3-month follow-up, the patient remained asymptomatic with normal bowel function and objective tests.<h4>Lessons</h4>This case illuminates a novel, self-limiting cerebro-enteral pathway activated by hypoglycemia, which we hypothesize is mediated by blood-brain barrier-disruption and corticotropin-releasing hormone-driven neurohumoral cascades.