Histopathology confirmed MALT lymphoma with immunophenotyping positive for CD20, BCL2, and myeloid cell nuclear differentiation antigen, and negative for CD5, CD10, and Cyclin D1.<h4>Interventions</h4>The patient underwent orbital biopsy via the lamina papyracea, allowing safe access to the inferomedial orbit. The gene discussed is MNDA; the disease is MALT lymphoma.