Combined with the recursive feature elimination method, it identified 21 clinically relevant variables, including age, total protein, albumin, total bilirubin, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transpeptidase, glucose, lactate dehydrogenase, creatine kinase-MB, creatinine, potassium-chloride ratio, sodium ion, calcium ion, eosinophil count, hemoglobin, platelet count, Systemic Immune-Inflammation Index, Pan-Immune-Inflammation Value, platelet-lymphocyte ratio, and sodium-chloride ratio for RCC model construction. The gene discussed is ALB; the disease is renal cell carcinoma.