Mechanistically, BRG1 regulates cell growth by activating Wnt/β‐catenin signalling, which is characterised by a certain concentration of β‐catenin in the cytoplasm that is transported into the nucleus with the help of factors like Rac1, which has been shown to be necessary for stem cell maintenance, HPC expansion and the development of HCC [87]. This evidence concerns the gene SMARCA4 and hepatocellular carcinoma.