PLOD1 and polycystic ovary syndrome: PCOS mice exhibited hyperandrogenemia (free testosterone: 6.6 ± 0.5 vs. 3.9 ± 0.3 ng/mL) and LH elevation (31.0 ± 4.5 vs. 18.3 ± 3.5 mU/mL) versus controls (both P < 0.01).