TNF and polycystic ovary syndrome: Here we further examined inflammatory factors and it has been showed PCOS mice had markedly increased serum levels of IL-6 and TNF-α, and decreased serum level of IL-10, which were significantly reversed in BSTJF-H and FPS-ZM1 groups compared with PCOS group (all P < 0.05) (Fig. 7A-C).