Moreover, immune markers such as soluble urokinase plasminogen activator receptor (suPAR), interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP), soluble CD163 (sCD163), and neutrophil gelatinase-associated lipocalin (NGAL) are associated with systemic inflammation and have been suggested as potential markers for depression risk in various populations (Mudra Rakshasa-Loots 2023). This evidence concerns the gene LCN2 and major depressive disorder.