Additionally, Viardot et al. reported a lower PYY response after a carbohydrate-rich meal in individuals with a family history of T2DM but without IGT, compared to those without a family history of T2DM, whereas neither fasting PYY levels nor PYY AUC after a fat-rich meal differed between the two groups [136]. The gene discussed is PYY; the disease is type 2 diabetes mellitus.