While caspase‐3/GSDME‐dependent pyroptosis was observed following axitinib treatment in the mouse neuroblastoma 9464D cells, 975A2 cells, and 9464D implanted NB syngeneic mouse models [174], the NLRP3/caspase‐1/GSDMD pathway was found in the human neuroblastoma cell lines, IMR‐32 and SK‐N‐SH cells, with bisphenol A (BPA) treatment [73]. This evidence concerns the gene NLRP3 and neuroblastoma.