So, the primary set of biomarkers associated with skin cutaneous melanoma includes TEKT5, ZNF154, H2AC14, BX284668.6, MYCNOS, STUM, SERTM2, RPSAP18, REG4, PSCA, PAEP, ACTR3C, MSLN, MRPS18AP1, ISLR, IL37, IGLV3.16, H2BC11, GPR25, and MTND4P35. The gene discussed is ISLR; the disease is cutaneous melanoma.