IL10 and major depressive disorder: A study focusing on deployed military personnel suggested a tendency for depression to be linked with higher IL-10, an anti-inflammatory cytokine, in neuronal-derived exosomes from the peripheral blood.116 Vedantam et al.96 also found that higher plasma IL-10 at 6 months post-injury was significantly associated with more pronounced depression symptoms (CES-D) in acute mTBI.