ANLN and neoplasm: Sheng Li et al. found that ANLN knockdown led to an increased expression of inflammation-related molecules(including caspase-1, NLRP3, cleaved-GSDMD, IL-1β, ASC, and IL-18) in tumor cell lines, suggesting that ANLN inhibits LUAD progression by activating pyroptosis (Sheng et al., 2023).