↓ Steatosis; ↓ lipogenesis genes (Dgat2, Scd1, Srebp1c); ↑ lipid catabolism genes (Hsl, Acox); ↑ AMPK activation, ↑ CPT1A, ↑ PPARα; ↓ inflammatory genes (Mcp1, Il6, TNF-α, TLR4); ↓ ER stress markers; ↑ autophagy-related gene expression. The gene discussed is SCD; the disease is steatosis.