CD163 and colorectal carcinoma: Similarly, a significant difference was observed between the expression of CD68+ and CD163+ cells in patients and normal mucosa (CD68+: CRC I, II p < 0.001; CRC III, IV p < 0.0001, respectively), (CD163+: CRC I, II p < 0.01; CRC III, IV p < 0.001, respectively) (Figures 4B, C).