TNF and hypothyroidism: As shown in (Figures 5B, C) and Table 2, TSH, TPOAb, CRP, percentage of Th17 cells, Th17/Treg ratio, IL-2, IL-6, IL-10 and TNFα levels increased significantly in the hypothyroidism group compared to the control group, and FT4 levels and percentage of Treg cells decreased significantly.