These genes are tied to renal sodium-phosphate regulation (SCGN/SLC17A family), vascular remodeling (FGF5), neurogenic BP control (NGF), and TGF-β-mediated vascular signaling (TGFBR2), collectively suggesting renal and vascular pathways underlying HTN in admixed Hispanic populations. The gene discussed is FGF5; the disease is hypertensive disorder.