ALB and obesity due to melanocortin 4 receptor deficiency: For Patient A (who developed VTE), high-risk features such as hypoalbuminemia (Albumin = 1.9), extreme obesity (BMI = 36.6), and advanced age (Age = 75) collectively elevated the predicted value [f(x) = 2.0] above the baseline E[f(x)] = 1.16, strongly indicating a poor outcome.