TGFB1 and neoplasm: Since M2 macrophages promote tumorigenesis and metastasis via the EMT transcription factor Snail/TGF‐β pathway,37 shifting macrophage polarization toward the M1 phenotype and reducing the M2/M1 ratio may represent a novel multidimensional strategy to simultaneously target tumors and M2 tumor‐associated macrophages (TAMs).