Intriguingly, while shQKI‐MitoEVs reduced α‐SMA and Col1a1 mRNA levels in sham‐operated hearts (Figure 9d), this effect was lost post‐MI, with no significant differences in fibrotic mRNA levels between shQKI‐ and shNC‐MitoEV‐treated MI hearts (Figure 9d). The gene discussed is ACTA1; the disease is myocardial infarction.