NLRP3 and Atrophy: Consistent with the random forest model results, retinal NLRP3, CCasp3, and atrophy exhibited strong AUC values for disease diagnosis, with notable further improvements when combined with Aβ42 (0.92, 0.87, and 0.89, respectively; Fig. 6E and Supplementary Fig. 14B–D), including within individual diagnostic groups (Supplementary Fig. 15A–C).