TRPV1 and autoimmune disease: TRPV1 is a nonselective cation channel abundantly expressed in a wide array of cell types distributed throughout the body [8], and it has been reported that TRPV1 plays a role in the modulation of the immune system [9–11], consequently, investigations are examining the potential role of TRPV1 in the development and progression of autoimmune disorders [12].