This contrasts with samples from older animals, where these transcriptomic markers are clearly discriminating AFC from NPC (Foldchange > 1.3, 1.5, 1.4, 1.6 for ACAN, COL2A1, PAX1, CA12 in NPC and > 1.6, 1.4 for COL1A1, HTRA1 in AFC) (Figure S3C). Here, COL1A1 is linked to nasopharyngeal carcinoma.