The Mechanistic Target of Rapamycin (mTOR), Nuclear Factor Kappa-light-chain-enhancer of activated B cells (NF-κB), and AMP-activated protein kinase (AMPK) signaling pathways are interconnected; dysregulation of these pathways contributes to age-related muscle atrophy, whereas their appropriate modulation by exercise supports muscle mass maintenance and may help prevent sarcopenia (Li et al., 1998; Cai et al., 2004; Zeng et al., 2020; Tang et al., 2019). Here, MTOR is linked to age.