Moreover, both live, pasteurized, and powdered forms of AKM Lab-01 enhanced GLP-1 expression, with Amuc_1100 protein content at 350 ng/mg in viable preparations and 450 ng/mg in drug substance form; the strain also reduced serum LPS, TNF-α and IL-6 levels, which contributed to the improvement of obesity and associated metabolic disorders. This evidence concerns the gene GCG and obesity due to melanocortin 4 receptor deficiency.