It was shown earlier (Jurgens et al., 2012), that proinflammatory cytokines (IL-1β, IL-6, TNF-α, IFN-α) and microglial reactivity were increased, while neurotrophic (BDNF, NGF) and immunomodulatory (CD200, CX3CL1) factors were decreased in the hippocampus of influenza infected adult mice. This evidence concerns the gene IL1B and influenza.