CSF3 and pneumonia: For instance, mouse adapted strain A/California/07/2009 (H1N1pdm09) was shown to induce maternal mortality and morbidity, severe pneumonia with immune cells infiltration; miscarriage, as well as reduced serum and uterine progesterone; elevated lungs IL-1α, IL-6, G-CSF, and chemokines in pregnant BALB/c mice (Kim et al., 2012).