CASP8 and schizophrenia: CASP1 (F4,32.47 = 3.79, p = .012), CASP8 (F4,34.21 = 3.30, p = .022) and P53 mRNAs were increased in high-inflammation schizophrenia compared with low- (CASP1 and P53) and high- (CASP1 and CASP8) inflammation bipolar subgroups (all p adj.