FAS and early-onset autosomal dominant Alzheimer disease: Although expression of TNFR1 in astrocytes has not been found in other central nervous system (CNS) disorders, astrocytes express FAS in inflammatory-related neurodegenerative diseases such as Alzheimer’s disease (72), Parkinson’s disease (73), Huntington’s disease (73), and autoimmune encephalitis (74), similar to what we found here in schizophrenia and bipolar disorder.