CASP8 and schizophrenia: Furthermore, the means for mRNA encoding cell death–related proteins acting downstream of TNF receptors (P53, CASP1, CASP7, CASP8; all ps ≤ .05) were increased in high-inflammation schizophrenia, as were mRNAs encoding proteins regulating cell survival (BCL2 and MCL1, all ps ≤ .01).