A lower ratio indicates a better balance between atherogenic and protective lipoproteins, which correlates with a lower risk of ASCVD.16 Recent studies have also emphasised this ratio as a more accurate predictor of cardiovascular events than traditional lipid measurements.17 Advances in genomics have revealed that genetic variations influence Apo A1 and Apo B levels, affecting ASCVD.18,19,20. Here, APOB is linked to atherosclerosis.