Univariate analysis demonstrated a significant association between pCR and age <50 years (p = 0.004), tumor size <5 cm (p = 0.005), lymphatic invasion (p = 0.001), nuclear grade 3 (p = 0.003), vascular invasion (p = 0.001), and Ki-67 index ≥35% (p < 0.001). This evidence concerns the gene MKI67 and neoplasm.